Anxiety disorders Įscitalopram appears to be effective in treating generalized anxiety disorder, with relapse on escitalopram at 20% rather than placebo at 50%, which translates to a number needed to treat of 3.33. As of 2012, reviews had concluded (with caveats in some cases) that escitalopram is modestly superior to citalopram in efficacy and tolerability. Accordingly, this issue has been examined in at least 10 different systematic reviews and meta analyses. The importance of this issue followed from the greater cost of escitalopram relative to the generic mixture of isomers of citalopram, prior to the expiration of the escitalopram patent in 2012, which led to charges of evergreening. Ĭontroversy existed regarding the effectiveness of escitalopram compared with its predecessor, citalopram. It is also the safest one to give to children and adolescents. Depression Įscitalopram is among the most effective and well-tolerated antidepressants for the short-term (acute) treatment of major depressive disorder in adults. In Australia it is approved for major depressive disorder. In European countries and the United Kingdom, it is approved for depression (MDD) and anxiety disorders these include: general anxiety disorder (GAD), social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), and panic disorder with or without agoraphobia. Medical uses Įscitalopram has FDA approval for the treatment of major depressive disorder in adolescents and adults, and generalized anxiety disorder in adults. In 2020, it was the fifteenth most commonly prescribed medication in the United States, with more than 30 million prescriptions. It is on the World Health Organization's List of Essential Medicines. Escitalopram is rarely replaced by twice the dose of citalopram, though escitalopram is safer and more effective. Įscitalopram was approved for medical use in the United States in 2002. Escitalopram is the ( S)- enantiomer of citalopram (which exists as a racemate), hence the name es-citalopram. It is unclear if use during pregnancy or breastfeeding is safe. More serious side effects may include suicidal thoughts in people up to the age of 24 years. It is taken by mouth, available commercially as an oxalate salt exclusively.Ĭommon side effects include trouble sleeping, nausea, sexual problems, and feeling tired. Escitalopram is mainly used to treat major depressive disorder and generalized anxiety disorder. Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.
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